LGALS8

Across TCGA cell cohorts, LGALS8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,806 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LGALS8-associated GO terms across cancer lineages are Xenophagy, Membrane fission, and Post-Golgi vesicle-mediated transport. Each is linked with LGALS8 in more than 17 cancer types. Because this analysis shows association rather than direction, both LGALS8-to-partner and partner-to-LGALS8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Xenophagy grouped by LGALS8-low versus LGALS8-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS8→partner) and Y-score (partner→LGALS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Xenophagy →	+0.254	+1.871	<.001	<.001	3	18
STOMACH	Membrane fission →	+0.054	+1.304	.003	<.001	3	11
STOMACH	Post-Golgi vesicle-mediated transport →	+0.060	+1.095	.002	.002	3	10
STOMACH	Nuclear membrane organization →	+0.079	+1.157	.001	.006	2	11
STOMACH	Nuclear membrane reassembly →	+0.089	+1.360	.002	.006	3	9
LUNG_SCLC	Nuclear envelope organization →	+0.070	+1.600	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,806 associations by consensus.

Xenophagy by LGALS8 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →