LGALS7B

Across TCGA patient cohorts, LGALS7B RNA expression is significantly associated with the go_rna of many other GO terms, with 7,047 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible LGALS7B-associated GO terms across cancer lineages are Intermediate filament bundle assembly, Keratinization, and Nucleolar large rRNA transcription by RNA polymerase I. Each is linked with LGALS7B in more than 13 cancer types. Because this analysis shows association rather than direction, both LGALS7B-to-partner and partner-to-LGALS7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intermediate filament bundle assembly grouped by LGALS7B-low versus LGALS7B-high in SKCM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS7B→partner) and Y-score (partner→LGALS7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Intermediate filament bundle assembly →	+0.201	+2.040	<.001	<.001	3	14
ESCA	Keratinization →	+0.218	+4.053	<.001	<.001	3	13
STAD	Nucleolar large rRNA transcription by RNA polymerase I →	+0.049	+1.098	<.001	<.001	3	13
TGCT	Plasma membrane raft assembly →	+0.093	+1.197	<.001	<.001	3	13
ESCA	Establishment of skin barrier →	+0.066	+2.388	<.001	<.001	3	12
ESCA	Satellite cell activation involved in skeletal muscle regeneration →	+0.146	+3.899	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,047 associations by consensus.

Intermediate filament bundle assembly by LGALS7B expression — SKCM

Explore this box plot interactively →