LGALS7B

Across TCGA cell cohorts, LGALS7B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,155 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible LGALS7B-associated GO terms across cancer lineages are Transepithelial water transport, siRNA processing, and Glucocorticoid metabolic process. Each is linked with LGALS7B in more than 5 cancer types. Because this analysis shows association rather than direction, both LGALS7B-to-partner and partner-to-LGALS7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transepithelial water transport grouped by LGALS7B-low versus LGALS7B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS7B→partner) and Y-score (partner→LGALS7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Transepithelial water transport →	+2.234	+2.277	<.001	.001	3	6
BLOOD_Myeloma	siRNA processing →	+0.118	+0.068	.002	.003	3	5
LARGE_INTESTINE	Glucocorticoid metabolic process →	-0.187	-0.772	.001	.005	3	5
OESOPHAGUS	Negative regulation of mRNA processing →	+0.121	+3.995	.001	.004	3	5
PANCREAS	Positive regulation of neurotransmitter secretion →	-0.078	-0.925	.005	.003	3	5
OESOPHAGUS	Methylation →	+0.047	+3.410	.001	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,155 associations by consensus.

Transepithelial water transport by LGALS7B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →