LGALS7B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LGALS7B protein abundance is significantly associated with the RNA expression of many other genes, with 877 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LGALS7B-associated genes across cancer lineages are ZNF624, CLDND2, and BMT2. Each is linked with LGALS7B in more than 2 cancer types. Because this analysis shows association rather than direction, both LGALS7B-to-partner and partner-to-LGALS7B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS7B versus ZNF624 in LUNG_NSCLC_LUAD, with a Pearson correlation of 0.91.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS7B→partner) and Y-score (partner→LGALS7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADZNF624 →+0.350+3.483.003<.00133
LUNG_NSCLC_LUADCLDND2 →+1.200+3.483<.001<.00132
BLOOD_LymphomaBMT2 →+1.215+2.990.006.00423
OESOPHAGUSKIFC1 →+0.727+4.445.002.00923
OESOPHAGUSRPAP3 →+1.415+6.050<.001<.00132
LUNG_NSCLC_LUADZMAT5 →+0.710+3.483.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 877 associations by consensus.

LGALS7B vs ZNF624 — LUNG_NSCLC_LUAD

Per-sample scatter of LGALS7B vs ZNF624 in LUNG_NSCLC_LUAD (Pearson r = 0.91).

Explore this scatter interactively →

Exploration