LGALS7B

Across TCGA cell cohorts, LGALS7B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LGALS7B-associated genes across cancer lineages are MBD3L2B, GUCA2A, and KRTAP7-1. Each is linked with LGALS7B in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS7B-to-partner and partner-to-LGALS7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MBD3L2B grouped by LGALS7B-low versus LGALS7B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS7B→partner) and Y-score (partner→LGALS7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MBD3L2B →	+0.019	+4.969	<.001	.003	3	1
BLOOD_Leukemia	GUCA2A →	+0.039	+4.969	<.001	.003	3	1
BLOOD_Leukemia	KRTAP7-1 →	+0.071	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MBD3L2B by LGALS7B expression — BLOOD_Leukemia

Explore this box plot interactively →