LGALS7B

Across TCGA cell cohorts, LGALS7B mutation is significantly associated with the mutation status of many other genes, with 237 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LGALS7B-associated genes across cancer lineages are RASD2, RANGAP1, and CTSZ. Each is linked with LGALS7B in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS7B-to-partner and partner-to-LGALS7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RASD2 grouped by LGALS7B-low versus LGALS7B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS7B→partner) and Y-score (partner→LGALS7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RASD2 →	+4.309	+4.560	.007	.007	1	1
BLOOD_Leukemia	RANGAP1 →	+4.309	+4.560	.007	.007	1	1
BLOOD_Leukemia	CTSZ →	+4.309	+4.560	.007	.007	1	1
BLOOD_Leukemia	KCND1 →	+4.309	+4.560	.007	.007	1	1
BLOOD_Leukemia	RS1 →	+4.309	+4.560	.007	.007	1	1
BLOOD_Leukemia	ACP5 →	+4.894	+5.870	<.001	<.001	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 237 associations by consensus.

RASD2 by LGALS7B expression — BLOOD_Leukemia

Explore this box plot interactively →