LGALS4

Across TCGA patient cohorts, LGALS4 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,814 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LGALS4-associated proteins across cancer lineages are EIF4G1, RAB31, and COQ7. Each is linked with LGALS4 in more than 3 cancer types. Because this analysis shows association rather than direction, both LGALS4-to-partner and partner-to-LGALS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS4 versus EIF4G1 in GBM, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS4→partner) and Y-score (partner→LGALS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EIF4G1 →	-0.243	-0.199	<.001	.001	3	4
PDAC	RAB31 →	-0.507	-1.507	<.001	<.001	3	4
PDAC	COQ7 →	+0.375	+1.255	<.001	<.001	3	4
PDAC	HIP1R →	+0.385	+1.456	<.001	<.001	3	4
BRCA	RING1 →	+0.295	+0.311	<.001	.009	3	3
LUAD	SH3BGRL2 →	+0.426	+1.915	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,814 associations by consensus.

LGALS4 vs EIF4G1 — GBM

Explore this scatter interactively →