LGALS4

Across TCGA patient cohorts, LGALS4 protein abundance is significantly associated with the RNA expression of many other genes, with 6,340 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LGALS4-associated genes across cancer lineages are FAM83E, CYP2C18, and SLC9A2. Each is linked with LGALS4 in more than 2 cancer types. Because this analysis shows association rather than direction, both LGALS4-to-partner and partner-to-LGALS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LGALS4 versus FAM83E in PDAC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS4→partner) and Y-score (partner→LGALS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	FAM83E →	+0.780	+0.584	<.001	<.001	3	3
LUAD	CYP2C18 →	+1.067	+1.280	<.001	<.001	3	3
PDAC	SLC9A2 →	+1.093	+0.671	<.001	<.001	3	3
PDAC	NR0B2 →	+1.362	+0.674	<.001	<.001	3	3
PDAC	HMGCS2 →	+1.939	+0.681	<.001	<.001	3	3
PDAC	SSTR1 →	+0.606	+0.554	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,340 associations by consensus.

LGALS4 vs FAM83E — PDAC

Explore this scatter interactively →