LGALS16

Across TCGA patient cohorts, LGALS16 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,499 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LGALS16-associated GO terms across cancer lineages are Mitochondrial respiratory chain complex assembly, Oxaloacetate metabolic process, and Oxidative phosphorylation. Each is linked with LGALS16 in more than 7 cancer types. Because this analysis shows association rather than direction, both LGALS16-to-partner and partner-to-LGALS16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial respiratory chain complex assembly grouped by LGALS16-low versus LGALS16-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS16→partner) and Y-score (partner→LGALS16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial respiratory chain complex assembly →	+0.117	+0.099	<.001	<.001	3	8
STAD	Oxaloacetate metabolic process →	+0.068	+0.066	<.001	<.001	3	7
STAD	Oxidative phosphorylation →	+0.127	+0.094	<.001	<.001	3	7
STAD	Aerobic respiration →	+0.129	+0.100	<.001	<.001	3	7
STAD	NADH dehydrogenase complex assembly →	+0.118	+0.089	<.001	<.001	3	7
STAD	Negative regulation of establishment of protein localization →	+0.082	+0.089	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,499 associations by consensus.

Mitochondrial respiratory chain complex assembly by LGALS16 expression — STAD

Explore this box plot interactively →