LGALS16

Across TCGA cell cohorts, LGALS16 RNA expression is significantly associated with the mutation status of many other genes, with 47 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LGALS16-associated genes across cancer lineages are FOLH1, DYNC2H1, and SLC12A4. Each is linked with LGALS16 in more than 1 cancer types. Because this analysis shows association rather than direction, both LGALS16-to-partner and partner-to-LGALS16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOLH1 grouped by LGALS16-low versus LGALS16-high in LUNG_SCLC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LGALS16→partner) and Y-score (partner→LGALS16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	FOLH1 →	+4.817	+0.148	.001	<.001	3	2
PANCREAS	DYNC2H1 →	+4.029	+0.020	.007	<.001	3	1
OESOPHAGUS	SLC12A4 →	+4.906	+0.046	.006	<.001	3	1
OESOPHAGUS	U2SURP →	+4.906	+0.046	.006	<.001	3	1
OESOPHAGUS	OR1L8 →	+4.906	+0.046	.006	<.001	3	1
OESOPHAGUS	PNPLA1 →	+4.906	+0.046	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

FOLH1 by LGALS16 expression — LUNG_SCLC

Explore this box plot interactively →