LFNG

Across TCGA patient cohorts, LFNG RNA expression is significantly associated with the protein abundance of many other proteins, with 15,111 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LFNG-associated proteins across cancer lineages are GPAT3_S68, THSD4, and THUMPD1. Each is linked with LFNG in more than 3 cancer types. Because this analysis shows association rather than direction, both LFNG-to-partner and partner-to-LFNG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LFNG versus GPAT3_S68 in OV, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LFNG→partner) and Y-score (partner→LFNG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GPAT3_S68 →	-0.863	-0.904	.003	.004	3	4
BRCA	THSD4 →	+0.786	+1.118	<.001	<.001	3	4
BRCA	THUMPD1 →	+0.281	+0.954	.001	.005	3	4
PDAC	TNRC18_S1127 →	+0.987	+0.603	<.001	<.001	3	4
BRCA	CLASP1_S559 →	-0.752	-1.544	<.001	<.001	3	4
BRCA	DHRS3 →	-0.577	-1.194	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,111 associations by consensus.

LFNG vs GPAT3_S68 — OV

Explore this scatter interactively →