LFNG

Across TCGA cell cohorts, LFNG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,165 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LFNG-associated GO terms across cancer lineages are Regulation of somitogenesis, Regulation of gastrulation, and Mature B cell differentiation involved in immune response. Each is linked with LFNG in more than 19 cancer types. Because this analysis shows association rather than direction, both LFNG-to-partner and partner-to-LFNG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of somitogenesis grouped by LFNG-low versus LFNG-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LFNG→partner) and Y-score (partner→LFNG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of somitogenesis →	+1.832	+3.288	<.001	<.001	3	20
OVARY	Regulation of gastrulation →	-0.206	-2.093	<.001	<.001	3	12
KIDNEY	Mature B cell differentiation involved in immune response →	+0.182	+2.955	<.001	.001	3	10
LUNG_SCLC	Marginal zone B cell differentiation →	+0.333	+1.885	.004	<.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of gastrulation →	-0.296	-1.978	.001	<.001	3	10
PANCREAS	Positive regulation of matrix metallopeptidase secretion →	-0.258	-2.035	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,165 associations by consensus.

Regulation of somitogenesis by LFNG expression — BONE

Explore this box plot interactively →