LEXM

Across TCGA patient cohorts, LEXM RNA expression is significantly associated with the protein abundance of many other proteins, with 12,049 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LEXM-associated proteins across cancer lineages are UMPS, CDH1, and HK2. Each is linked with LEXM in more than 4 cancer types. Because this analysis shows association rather than direction, both LEXM-to-partner and partner-to-LEXM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LEXM versus UMPS in PDAC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LEXM→partner) and Y-score (partner→LEXM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	UMPS →	+0.318	+0.451	<.001	<.001	3	4
LSCC	CDH1 →	+0.591	+0.766	<.001	<.001	3	4
LSCC	HK2 →	+0.527	+0.520	<.001	<.001	3	4
LSCC	MFN1 →	+0.344	+0.598	<.001	<.001	3	4
OV	STX2 →	-0.507	-0.676	<.001	<.001	3	4
HNSC	EPB41L1_T475 →	+0.614	+0.717	.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,049 associations by consensus.

LEXM vs UMPS — PDAC

Explore this scatter interactively →