Across TCGA patient cohorts, LEUTX mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LEUTX-associated genes across cancer lineages are RNU4-13P, MIR6511A1, and DEFB108E. Each is linked with LEUTX in more than 1 cancer types. Because this analysis shows association rather than direction, both LEUTX-to-partner and partner-to-LEUTX results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LEUTX→partner) and Y-score (partner→LEUTX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-13P →	+0.191	+4.464	<.001	.005	3	2
BRCA	MIR6511A1 →	+0.373	+8.471	<.001	.005	3	1
BRCA	DEFB108E →	+0.108	+8.055	<.001	.007	3	1
BRCA	VN1R33P →	+0.034	+8.471	<.001	.005	3	1
BRCA	RNA5SP446 →	+0.286	+8.471	<.001	.005	3	1
UCEC	MIR7702 →	+0.469	+5.475	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

LEUTX survival (RNA) · tumor vs normal (RNA) · all LEUTX data types