LEMD2

Across TCGA patient cohorts, LEMD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,467 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LEMD2-associated proteins across cancer lineages are NUP153, DEK, and CMTR1. Each is linked with LEMD2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LEMD2-to-partner and partner-to-LEMD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LEMD2 versus NUP153 in LSCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LEMD2→partner) and Y-score (partner→LEMD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NUP153 →	+0.345	+0.515	<.001	<.001	3	6
OV	DEK →	+0.329	+0.357	.001	<.001	3	6
OV	CMTR1 →	+0.480	+0.581	<.001	<.001	3	6
OV	ABCF1 →	+0.397	+0.590	<.001	<.001	3	6
LSCC	WRNIP1 →	+0.503	+0.414	<.001	<.001	3	5
LSCC	CDKAL1 →	+0.451	+0.533	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,467 associations by consensus.

LEMD2 vs NUP153 — LSCC

Explore this scatter interactively →