LEMD1-DT

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LEMD1-DT RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated LEMD1-DT data layer.

The strongest signal is observed in thymoma (THYM), where higher LEMD1-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LEMD1-DT expression acts as an unfavorable survival marker, although some lineages such as HNSC and STAD show a favorable association.

THYM, HNSC, and KIRP are the cancer types where LEMD1-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THYMDFSMedianII,III,IV0.7790.987<.00169view →
HNSCOSQuartileII,III,IV0.4560.321.00367view →
KIRPOSMedianAll0.5850.768<.00160view →
STADDFSMedianII,III,IV0.5330.275.00448view →
CESCOSTertileIII,IV0.7680.268<.00142view →
LGGOSMedianAll0.7330.884<.00142view →
SKCMOSQuartileAll0.8470.733.00228view →
OVOSTertileII,III,IV0.7450.662.02920view →
KIRCDFSQuartileAll0.7230.828.00419view →
READOSQuartileII,III,IV0.5590.869.00118view →
LIHCOSTertileII,III,IV0.5460.737.01914view →
PAADDFSQuartileAll0.2730.512.0179view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration