Across TCGA patient cohorts, LELP1 mutation is significantly associated with the RNA expression of many other genes, with 234 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible LELP1-associated genes across cancer lineages are FABP3P2, MIR4643, and RNA5SP414. Each is linked with LELP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LELP1-to-partner and partner-to-LELP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LELP1→partner) and Y-score (partner→LELP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FABP3P2 →	+0.411	+5.790	<.001	.003	3	2
SKCM	MIR4643 →	+0.143	+3.716	<.001	.001	3	2
UCEC	RNA5SP414 →	+1.378	+3.840	<.001	.007	3	1
SKCM	CYCSP53 →	+0.092	+2.771	<.001	.003	3	1
SKCM	LINC01563 →	+0.987	+2.006	.002	.005	3	1
SKCM	OR7E7P →	-0.417	-3.575	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 234 associations by consensus.

Exploration

LELP1 survival (RNA) · tumor vs normal (RNA) · all LELP1 data types