Across TCGA pan-cancer cohorts, LELP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LELP1’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LELP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LELP1 is over-expressed in tumor.
HNSC and LUSC are the cancer types where LELP1 tumor–normal differential expression is most reproducible.