LEFTY2

Across TCGA patient cohorts, LEFTY2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,435 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LEFTY2-associated proteins across cancer lineages are PPP1R12B, LMOD1, and SH3D19. Each is linked with LEFTY2 in more than 7 cancer types. Because this analysis shows association rather than direction, both LEFTY2-to-partner and partner-to-LEFTY2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LEFTY2 versus PPP1R12B in UCEC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LEFTY2→partner) and Y-score (partner→LEFTY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP1R12B →	+0.869	+1.389	<.001	<.001	3	8
UCEC	LMOD1 →	+0.987	+1.478	<.001	<.001	3	8
UCEC	SH3D19 →	+0.484	+2.133	<.001	<.001	3	7
UCEC	SORBS1 →	+0.730	+1.091	<.001	<.001	3	7
UCEC	SYNPO2 →	+0.775	+1.408	<.001	<.001	3	7
COAD	TPM1 →	+0.696	+0.974	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,435 associations by consensus.

LEFTY2 vs PPP1R12B — UCEC

Explore this scatter interactively →