LDHC

Across TCGA cell cohorts, LDHC mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LDHC-associated genes across cancer lineages are ACSM6. Each is linked with LDHC in more than 1 cancer types. Because this analysis shows association rather than direction, both LDHC-to-partner and partner-to-LDHC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACSM6 grouped by LDHC-low versus LDHC-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDHC→partner) and Y-score (partner→LDHC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACSM6 →	+0.027	+4.584	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

ACSM6 by LDHC expression — LARGE_INTESTINE

Explore this box plot interactively →