LDHBP1

Across TCGA patient cohorts, LDHBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,498 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LDHBP1-associated GO terms across cancer lineages are Positive regulation of telomere maintenance, tRNA metabolic process, and Regulation of telomere maintenance. Each is linked with LDHBP1 in more than 19 cancer types. Because this analysis shows association rather than direction, both LDHBP1-to-partner and partner-to-LDHBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomere maintenance grouped by LDHBP1-low versus LDHBP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LDHBP1→partner) and Y-score (partner→LDHBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of telomere maintenance →	+0.070	+0.174	.001	<.001	3	20
STAD	tRNA metabolic process →	+0.063	+0.159	<.001	<.001	3	20
STAD	Regulation of telomere maintenance →	+0.066	+0.158	<.001	<.001	3	19
STAD	Methylation →	+0.056	+0.171	<.001	<.001	3	19
STAD	Macromolecule methylation →	+0.060	+0.160	<.001	<.001	3	19
STAD	Negative regulation of gene expression, epigenetic →	+0.065	+0.160	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,498 associations by consensus.

Positive regulation of telomere maintenance by LDHBP1 expression — ESCA

Explore this box plot interactively →