Q-omics provides the consensus-scored LDHBP1 profile across patient tissues and cancer cell-line models. LDHBP1 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, LDHBP1 is differentially expressed in 5, with the highest sampling consensus in KIRC. Additionally, LDHBP1 RNA expression shows 6,498 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight UCS, KIRC, and STAD as cancer lineages where LDHBP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LDHBP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LDHBP1 survival associations across molecular data types. LDHBP1 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LDHBP1 RNA expression–survival associations across cancer types. High LDHBP1 expression shows unfavorable associations in UCS, ACC, OV, MESO and UVM, but favorable associations in PAAD. The UCS Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify UCS as the clearest survival context for LDHBP1 RNA expression.
This table summarizes LDHBP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for LDHBP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LDHBP1 shows lower tumor expression in KIRC and THCA and higher tumor expression in COAD, LIHC and BLCA. The KIRC box plot shows higher LDHBP1 RNA expression in normal versus tumor tissue (log2 FC = −0.044, t-test p = .001).
This table shows molecular features associated with LDHBP1 in patient tissues and cancer cell lines. In patient samples, LDHBP1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
