lactate dehydrogenase A like 6F, pseudogeneGenealiases: []
Q-omics provides the consensus-scored LDHAL6FP profile across patient tissues and cancer cell-line models. LDHAL6FP expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, LDHAL6FP is differentially expressed in 5, with the highest sampling consensus in READ. Additionally, LDHAL6FP RNA expression shows 15,432 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight HNSC, READ, and TGCT as cancer lineages where LDHAL6FP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LDHAL6FP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LDHAL6FP survival associations across molecular data types. LDHAL6FP RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LDHAL6FP RNA expression–survival associations across cancer types. High LDHAL6FP expression shows unfavorable associations in KIRP, THCA and PCPG, but favorable associations in HNSC, MESO and LUAD. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify HNSC as the clearest survival context for LDHAL6FP RNA expression.
This table summarizes LDHAL6FP tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in READ for RNA.
This table ranks reproducible tumor–normal expression differences for LDHAL6FP. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LDHAL6FP shows lower tumor expression in THCA and higher tumor expression in READ, HNSC, LUAD and LUSC. The READ box plot shows higher LDHAL6FP RNA expression in tumor versus normal tissue (log2 FC = +0.248, t-test p = .017).
This table shows molecular features associated with LDHAL6FP in patient tissues and cancer cell lines. In patient samples, LDHAL6FP shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
