LDHAL6EP

Across TCGA pan-cancer cohorts, LDHAL6EP RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated LDHAL6EP data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher LDHAL6EP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LDHAL6EP expression acts as an unfavorable survival marker, although some lineages such as BLCA and MESO show a favorable association.

THCA, UCEC, and KICH are the cancer types where LDHAL6EP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.698	0.988	<.001	70	view →
UCEC	OS	Tertile	III,IV	0.725	0.844	.013	60	view →
KICH	DFS	Tertile	III,IV	0.183	0.761	.004	57	view →
BRCA	DFS	Tertile	III,IV	0.606	0.808	.015	24	view →
BLCA	OS	Tertile	III,IV	0.824	0.633	.015	21	view →
COAD	DFS	Tertile	III,IV	0.423	0.731	.005	18	view →
TGCT	DFS	Tertile	All	0.299	0.677	.041	18	view →
LIHC	DFS	Tertile	All	0.388	0.582	.003	18	view →
MESO	DFS	Quartile	II,III,IV	0.421	0.215	.018	15	view →
OV	OS	Tertile	III,IV	0.892	0.813	.020	14	view →
KIRP	DFS	Quartile	III,IV	0.814	0.471	.023	13	view →
KIRC	OS	Tertile	All	0.537	0.646	.019	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

LDHAL6EP–THCA (OS)

Open the THCA breakdown →