LDHAL6EP

Across TCGA pan-cancer cohorts, LDHAL6EP RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LDHAL6EP’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where LDHAL6EP RNA is repressed in tumor relative to normal tissue. In most cancer types LDHAL6EP is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

COAD, THCA, and READ are the cancer types where LDHAL6EP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LDHAL6EP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	IV	−0.146	<.001	10	view →
THCA	Male	All	−0.102	<.001	7	view →
READ	All	III,IV	−0.175	<.001	6	view →
LUSC	All	All	−0.065	<.001	5	view →
PRAD	All	All	+0.177	.007	2	view →
CHOL	All	All	+0.156	.030	1	view →
KIRC	Female	IV	+0.103	.028	1	view →
LUAD	All	III,IV	−0.073	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LDHAL6EP–COAD

Open the COAD breakdown →