LDHAL6B

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LDHAL6B mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated LDHAL6B data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher LDHAL6B mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated LDHAL6B expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC are the cancer types where LDHAL6B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSQuartileAll1.0000.519.01510view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

LDHAL6B–CCRCC (DFS)

Kaplan–Meier survival curve for LDHAL6B mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration