LDHAL6A

Across TCGA patient cohorts, LDHAL6A mutation is significantly associated with the RNA expression of many other genes, with 380 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LDHAL6A-associated genes across cancer lineages are CDY3P, OR4B2P, and RNU4-4P. Each is linked with LDHAL6A in more than 2 cancer types. Because this analysis shows association rather than direction, both LDHAL6A-to-partner and partner-to-LDHAL6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDY3P grouped by LDHAL6A-low versus LDHAL6A-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDHAL6A→partner) and Y-score (partner→LDHAL6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	CDY3P →	+0.050	+7.276	<.001	<.001	3	3
SKCM	OR4B2P →	+0.031	+4.591	<.001	<.001	3	2
UCEC	RNU4-4P →	+0.483	+3.193	<.001	<.001	3	2
UCEC	RNA5SP422 →	+0.871	+2.256	<.001	.006	3	2
READ	CDRT15P8 →	+0.125	+5.421	<.001	.005	3	1
READ	TMEM225 →	+0.114	+5.039	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 380 associations by consensus.

CDY3P by LDHAL6A expression — READ

Explore this box plot interactively →