LDB3

Across TCGA cell cohorts, LDB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,043 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible LDB3-associated GO terms across cancer lineages are Regulation of potassium ion transmembrane transport, tRNA transcription, and Regulation of TORC1 signaling. Each is linked with LDB3 in more than 7 cancer types. Because this analysis shows association rather than direction, both LDB3-to-partner and partner-to-LDB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of potassium ion transmembrane transport grouped by LDB3-low versus LDB3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LDB3→partner) and Y-score (partner→LDB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of potassium ion transmembrane transport →	-0.159	-0.236	<.001	.001	2	8
URINARY_TRACT	tRNA transcription →	+0.123	+0.271	<.001	.001	3	7
OESOPHAGUS	Regulation of TORC1 signaling →	+0.080	+0.438	<.001	<.001	3	7
STOMACH	Endosomal transport →	+0.083	+0.441	<.001	.003	3	6
OESOPHAGUS	Regulation of myoblast fusion →	+0.119	+0.305	.006	.001	3	6
STOMACH	Regulation of organelle assembly →	+0.061	+0.392	<.001	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,043 associations by consensus.

Regulation of potassium ion transmembrane transport by LDB3 expression — OVARY

Explore this box plot interactively →