Across TCGA patient cohorts, LDB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,798 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LDB1-associated proteins across cancer lineages are P4HB, MYDGF, and VPS35. Each is linked with LDB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LDB1-to-partner and partner-to-LDB1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LDB1→partner) and Y-score (partner→LDB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	P4HB →	-0.606	-0.491	<.001	<.001	3	7
CCRCC	MYDGF →	-0.491	-0.402	<.001	<.001	3	5
PDAC	VPS35 →	+0.201	+0.280	<.001	.001	3	5
GBM	HSPA5 →	-0.300	-0.322	<.001	<.001	3	5
GBM	OGA →	+0.312	+0.384	<.001	<.001	3	5
GBM	PDIA4 →	-0.340	-0.362	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,798 associations by consensus.

Exploration

LDB1 survival (RNA) · tumor vs normal (RNA) · all LDB1 data types