LCORL

Across TCGA patient cohorts, LCORL mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCORL-associated genes across cancer lineages are Tuberin. Each is linked with LCORL in more than 1 cancer types. Because this analysis shows association rather than direction, both LCORL-to-partner and partner-to-LCORL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tuberin grouped by LCORL-low versus LCORL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCORL→partner) and Y-score (partner→LCORL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Tuberin →	+0.504	+2.817	.002	.036	2	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Tuberin by LCORL expression — UCEC

Explore this box plot interactively →