LCN8

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LCN8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,881 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LCN8-associated GO terms across cancer lineages are Regulation of calcium ion export across plasma membrane, Protein stabilization, and Positive regulation of pattern recognition receptor signaling pathway. Each is linked with LCN8 in more than 12 cancer types. Because this analysis shows association rather than direction, both LCN8-to-partner and partner-to-LCN8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN8→partner) and Y-score (partner→LCN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRegulation of calcium ion export across plasma membrane →+0.053+0.146<.001<.001313
STADProtein stabilization →+0.065+0.134<.001<.001313
STADPositive regulation of pattern recognition receptor signaling pathway →+0.055+0.132<.001<.001312
STADRegulation of membrane permeability →+0.067+0.139<.001<.001312
STADRegulation of protein localization to plasma membrane →+0.063+0.134<.001<.001312
STADPositive regulation of establishment of protein localization to mitochondrion →+0.068+0.145<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,881 associations by consensus.

Exploration