Across TCGA cell cohorts, LCN8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,001 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LCN8-associated GO terms across cancer lineages are Alcohol biosynthetic process, Tyrosine metabolic process, and Pyrimidine nucleoside monophosphate catabolic process. Each is linked with LCN8 in more than 4 cancer types. Because this analysis shows association rather than direction, both LCN8-to-partner and partner-to-LCN8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN8→partner) and Y-score (partner→LCN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Alcohol biosynthetic process →	+0.094	+0.043	.001	.005	3	5
BLOOD_Leukemia	Tyrosine metabolic process →	-0.174	-1.082	<.001	.007	3	5
BLOOD_Leukemia	Pyrimidine nucleoside monophosphate catabolic process →	-0.188	-1.316	<.001	<.001	3	5
BLOOD_Leukemia	Pyrimidine deoxyribonucleoside monophosphate catabolic process →	-0.188	-1.316	<.001	<.001	3	5
BLOOD_Lymphoma	Oncostatin-M-mediated signaling pathway →	-0.137	-0.928	<.001	.004	3	4
BLOOD_Lymphoma	Peptide metabolic process →	-0.062	-0.821	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,001 associations by consensus.

Exploration

LCN8 survival (RNA) · tumor vs normal (RNA) · all LCN8 data types