LCN6

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LCN6 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,988 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LCN6-associated proteins across cancer lineages are IL33, KANK3, and LDB3. Each is linked with LCN6 in more than 5 cancer types. Because this analysis shows association rather than direction, both LCN6-to-partner and partner-to-LCN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LCN6 versus IL33 in UCEC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN6→partner) and Y-score (partner→LCN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECIL33 →+0.725+0.149<.001<.00136
CCRCCKANK3 →+0.491+0.107<.001.00336
UCECLDB3 →+0.673+0.234.002.00336
OVMMRN2 →+0.611+0.059<.001.00436
OVKANK2_S540 →+0.575+0.046.001.00236
BRCATNS2_S120 →+0.554+0.190<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,988 associations by consensus.

LCN6 vs IL33 — UCEC

Per-sample scatter of LCN6 vs IL33 in UCEC (Pearson r = 0.42).

Explore this scatter interactively →

Exploration