LCN6

Across TCGA pan-cancer cohorts, LCN6 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated LCN6 data layer compared with 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LCN6 RNA is associated with better overall survival. In most high-consensus cancer types, elevated LCN6 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LIHC show a favorable association.

LUAD, LIHC, and OV are the cancer types where LCN6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	0.538	0.321	<.001	75	view →
LIHC	DFS	Tertile	All	0.650	0.415	<.001	70	view →
OV	OS	Tertile	IV	0.586	0.861	.012	36	view →
THCA	DFS	Quartile	All	0.939	0.783	.001	36	view →
CESC	DFS	Quartile	All	0.693	0.443	.001	34	view →
KIRC	OS	Tertile	All	0.880	0.770	<.001	33	view →
PAAD	DFS	Tertile	All	0.438	0.279	.010	32	view →
MESO	OS	Median	II,III,IV	0.320	0.725	.002	29	view →
KIRP	DFS	Tertile	IV	0.528	0.036	.003	29	view →
SARC	OS	Median	All	0.718	0.453	.004	23	view →
LAML	DFS	Tertile	All	0.213	0.602	.004	22	view →
BLCA	DFS	Median	All	0.503	0.177	.004	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

LCN6–LUAD (OS)

Open the LUAD breakdown →