LCN6

Across TCGA cell cohorts, LCN6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,539 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LCN6-associated GO terms across cancer lineages are Regulation of trophoblast cell migration, Positive regulation of stem cell differentiation, and Ascorbate homeostasis. Each is linked with LCN6 in more than 3 cancer types. Because this analysis shows association rather than direction, both LCN6-to-partner and partner-to-LCN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of trophoblast cell migration grouped by LCN6-low versus LCN6-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN6→partner) and Y-score (partner→LCN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of trophoblast cell migration →	+0.132	+0.037	<.001	.001	3	4
BLOOD_Leukemia	Positive regulation of stem cell differentiation →	+0.180	+3.410	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Ascorbate homeostasis →	-0.094	-0.022	.001	.007	3	3
LUNG_NSCLC_LUAD	Regulation of cellular response to transforming growth factor beta stimulus →	+0.054	+0.021	<.001	.003	3	3
LUNG_NSCLC_LUAD	Signal transduction in response to DNA damage →	+0.033	+0.021	.005	.008	3	3
BLOOD_Leukemia	COP9 signalosome assembly →	-0.162	-3.561	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,539 associations by consensus.

Regulation of trophoblast cell migration by LCN6 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →