LCN6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LCN6 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LCN6-associated genes across cancer lineages are SMIM31. Each is linked with LCN6 in more than 1 cancer types. Because this analysis shows association rather than direction, both LCN6-to-partner and partner-to-LCN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM31 grouped by LCN6-low versus LCN6-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCN6→partner) and Y-score (partner→LCN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaSMIM31 →+0.027+4.276<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SMIM31 by LCN6 expression — BLOOD_Leukemia

Box plot of SMIM31 in LCN6-low vs LCN6-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration