LCE6A

Across TCGA patient cohorts, LCE6A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,649 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LCE6A-associated GO terms across cancer lineages are Skin epidermis development, Regulation of epidermis development, and Epidermal cell differentiation. Each is linked with LCE6A in more than 9 cancer types. Because this analysis shows association rather than direction, both LCE6A-to-partner and partner-to-LCE6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skin epidermis development grouped by LCE6A-low versus LCE6A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE6A→partner) and Y-score (partner→LCE6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Skin epidermis development →	+0.074	+0.098	<.001	<.001	3	10
STAD	Regulation of epidermis development →	+0.074	+0.114	<.001	<.001	3	10
ESCA	Epidermal cell differentiation →	+0.063	+0.213	<.001	<.001	3	9
STAD	Cellular response to gamma radiation →	+0.092	+0.098	<.001	<.001	3	8
ESCA	Peptide cross-linking →	+0.126	+0.220	<.001	<.001	3	7
ESCA	Keratinocyte differentiation →	+0.074	+0.230	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,649 associations by consensus.

Skin epidermis development by LCE6A expression — STAD

Explore this box plot interactively →