LCE6A

Across TCGA pan-cancer cohorts, LCE6A RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LCE6A’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LCE6A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LCE6A is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUSC and THCA are the cancer types where LCE6A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LCE6A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.040	.006	3	view →
THCA	All	All	−0.011	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

LCE6A–LUSC

Open the LUSC breakdown →