LCE6A

Across TCGA cell cohorts, LCE6A RNA expression is significantly associated with the mutation status of many other genes, with 180 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LCE6A-associated genes across cancer lineages are UNC13C, XDH, and SON. Each is linked with LCE6A in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE6A-to-partner and partner-to-LCE6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UNC13C grouped by LCE6A-low versus LCE6A-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE6A→partner) and Y-score (partner→LCE6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	UNC13C →	+4.977	+0.030	.002	<.001	3	2
OESOPHAGUS	XDH →	+4.906	+0.060	.006	<.001	3	2
SOFT_TISSUE	SON →	+3.977	+0.020	.007	<.001	3	2
SOFT_TISSUE	SVIL →	+4.392	+0.024	.004	<.001	3	2
SOFT_TISSUE	COL5A2 →	+5.977	+0.040	.001	<.001	3	2
SOFT_TISSUE	COL19A1 →	+5.977	+0.040	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 180 associations by consensus.

UNC13C by LCE6A expression — SOFT_TISSUE

Explore this box plot interactively →