Across TCGA cell cohorts, LCE4A RNA expression is significantly associated with the mutation status of many other genes, with 48 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible LCE4A-associated genes across cancer lineages are TRPV6, DEUP1, and USF3. Each is linked with LCE4A in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE4A-to-partner and partner-to-LCE4A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE4A→partner) and Y-score (partner→LCE4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TRPV6 →	+4.022	+0.031	.006	<.001	3	1
SKIN	DEUP1 →	+4.437	+0.038	.004	<.001	3	1
SKIN	USF3 →	+3.700	+0.027	.009	<.001	3	1
SKIN	PCED1B →	+3.700	+0.027	.009	<.001	3	1
SKIN	FGD6 →	+4.437	+0.038	.004	<.001	3	1
SKIN	GDPGP1 →	+6.022	+0.063	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

LCE4A survival (RNA) · tumor vs normal (RNA) · all LCE4A data types