Across TCGA pan-cancer cohorts, LCE3E mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated LCE3E data layer compared with 16 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LCE3E mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated LCE3E expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC are the cancer types where LCE3E mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	II,III,IV	1.000	0.733	<.001	64	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: LCE3E tumor-vs-normal RNA expression · all LCE3E data types