Across TCGA patient cohorts, LCE3E RNA expression is significantly associated with the protein abundance of many other proteins, with 7,073 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LCE3E-associated proteins across cancer lineages are SPRR1B, A2ML1, and DEPTOR. Each is linked with LCE3E in more than 3 cancer types. Because this analysis shows association rather than direction, both LCE3E-to-partner and partner-to-LCE3E results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE3E→partner) and Y-score (partner→LCE3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SPRR1B →	+1.495	+0.481	<.001	<.001	3	4
UCEC	A2ML1 →	+1.170	+0.416	<.001	.007	3	3
HNSC	DEPTOR →	-0.511	-2.719	<.001	<.001	3	3
LSCC	FAM83H →	+0.647	+1.132	<.001	<.001	3	3
PDAC	FAM83H_S881 →	+0.849	+0.335	<.001	.003	3	3
LSCC	FSCN1 →	+0.426	+1.344	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,073 associations by consensus.

Exploration

LCE3E survival (RNA) · tumor vs normal (RNA) · all LCE3E data types