Across TCGA patient cohorts, LCE3E protein abundance is significantly associated with the RNA expression of many other genes, with 6,516 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LCE3E-associated genes across cancer lineages are TSPAN12, LYPD3, and KLK10. Each is linked with LCE3E in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE3E-to-partner and partner-to-LCE3E results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE3E→partner) and Y-score (partner→LCE3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TSPAN12 →	-1.559	-4.932	.003	<.001	3	2
LSCC	LYPD3 →	+2.004	+4.623	.003	.001	3	2
LSCC	KLK10 →	+4.442	+5.522	.002	<.001	3	2
LSCC	SELENBP1 →	-3.019	-5.001	<.001	<.001	3	2
LSCC	LCE3D →	+5.557	+5.305	<.001	<.001	3	2
LSCC	CRCT1 →	+3.475	+4.125	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,516 associations by consensus.

Exploration

LCE3E survival (RNA) · tumor vs normal (RNA) · all LCE3E data types