LCE3E

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LCE3E mutation is significantly associated with the RNA expression of many other genes, with 1,020 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible LCE3E-associated genes across cancer lineages are MIR7702, MIR4774, and GSKIP. Each is linked with LCE3E in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE3E-to-partner and partner-to-LCE3E results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE3E→partner) and Y-score (partner→LCE3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMIR7702 →+0.739+6.741<.001<.00132
READMIR4774 →+0.841+6.257<.001.00132
SKCMGSKIP →+0.665+3.372.006.00432
SKCMTM9SF1 →+0.558+3.591<.001.00132
SKCMMED1 →+0.700+3.604.002.00132
SKCMICE2 →+0.611+3.604.006.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,020 associations by consensus.

Exploration