Across TCGA patient cohorts, LCE3E mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. COAD shows the largest number of these associations.

The most reproducible LCE3E-associated genes across cancer lineages are CD4+ memory T-cells, CD4+ T-cells, and Th2 cells. Each is linked with LCE3E in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE3E-to-partner and partner-to-LCE3E results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE3E→partner) and Y-score (partner→LCE3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CD4+ memory T-cells →	+0.038	+2.958	<.001	.021	3	1
COAD	CD4+ T-cells →	+0.024	+5.419	<.001	.027	3	1
LUAD	Th2 cells →	+0.197	+2.819	.046	.036	3	1
SKCM	CLP →	+0.099	+3.604	.008	.001	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

LCE3E survival (RNA) · tumor vs normal (RNA) · all LCE3E data types