LCE3D

Across TCGA pan-cancer cohorts, LCE3D Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LCE3D data layer compared with 20 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher LCE3D Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LCE3D expression acts as an unfavorable survival marker.

READ and SKCM are the cancer types where LCE3D Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Median	IV	0.289	0.899	<.001	9	view →
SKCM	OS	Median	IV	0.415	0.861	.014	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

LCE3D–READ (OS)

Open the READ breakdown →