Across TCGA patient cohorts, LCE3B mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCE3B-associated genes across cancer lineages are MIR4727, RN7SL495P, and RN7SL453P. Each is linked with LCE3B in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE3B-to-partner and partner-to-LCE3B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE3B→partner) and Y-score (partner→LCE3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4727 →	+0.654	+4.551	<.001	.009	3	1
UCEC	RN7SL495P →	+0.304	+5.335	<.001	.003	3	1
SKCM	RN7SL453P →	+0.111	+5.212	<.001	.002	3	1
SKCM	FABP5P15 →	+0.157	+4.385	<.001	.008	3	1
SKCM	ATP6V0CP2 →	+0.174	+3.953	<.001	.005	3	1
LUAD	LSP1P3 →	+0.386	+4.481	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

LCE3B survival (RNA) · tumor vs normal (RNA) · all LCE3B data types