Across TCGA patient cohorts, LCE2D RNA expression is significantly associated with the go_rna of many other GO terms, with 5,142 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LCE2D-associated GO terms across cancer lineages are Peptidoglycan metabolic process, Keratinocyte proliferation, and Regulation of epidermis development. Each is linked with LCE2D in more than 6 cancer types. Because this analysis shows association rather than direction, both LCE2D-to-partner and partner-to-LCE2D results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE2D→partner) and Y-score (partner→LCE2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Peptidoglycan metabolic process →	+0.261	+0.701	<.001	<.001	3	6
ESCA	Keratinocyte proliferation →	+0.051	+0.174	<.001	<.001	2	7
ESCA	Regulation of epidermis development →	+0.046	+0.191	<.001	.009	2	7
CESC	Regulation of keratinocyte proliferation →	+0.029	+0.096	<.001	.001	3	5
ESCA	Peptide cross-linking →	+0.121	+0.305	<.001	<.001	2	6
SKCM	Regulation of antimicrobial humoral response →	+0.125	+0.771	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,142 associations by consensus.

Exploration

LCE2D survival (RNA) · tumor vs normal (RNA) · all LCE2D data types