LCE2D

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LCE2D mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCE2D-associated genes across cancer lineages are MSH2, Bcl-2, and Tuberin. Each is linked with LCE2D in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE2D-to-partner and partner-to-LCE2D results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE2D→partner) and Y-score (partner→LCE2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMSH2 →-0.543-2.973<.001.03532
UCECBcl-2 →-0.598-3.143.001.02031
UCECTuberin →+0.320+3.009.030.01921
UCECCaveolin-1 →-0.888-3.169.025.02011
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration