LCE2B

Across TCGA patient cohorts, LCE2B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,141 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LCE2B-associated GO terms across cancer lineages are Peptide cross-linking, Peptidoglycan metabolic process, and Skin epidermis development. Each is linked with LCE2B in more than 5 cancer types. Because this analysis shows association rather than direction, both LCE2B-to-partner and partner-to-LCE2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptide cross-linking grouped by LCE2B-low versus LCE2B-high in SKCM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE2B→partner) and Y-score (partner→LCE2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Peptide cross-linking →	+0.097	+0.915	<.001	<.001	3	6
ESCA	Peptidoglycan metabolic process →	+0.228	+0.402	<.001	<.001	3	6
BLCA	Skin epidermis development →	+0.024	+0.259	<.001	<.001	3	5
SKCM	Regulation of antimicrobial humoral response →	+0.121	+0.972	<.001	<.001	3	5
SKCM	Antimicrobial peptide production →	+0.271	+0.971	<.001	<.001	3	5
SKCM	Antibacterial peptide production →	+0.291	+0.984	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,141 associations by consensus.

Peptide cross-linking by LCE2B expression — SKCM

Explore this box plot interactively →